Previous studies suggested that patients of Psoriasis have an increased
frequency of a variety of cardiovascular and diabetic co-morbidities. Limited population
based data exist on this association and few studies have determined which factors are
associated with Psoriasis.
To evaluate the association between Psoriasis and risk of Diabetes Mellitus and
Hypertension.
A case control study among psoriatic and non-psoriatic patients who were attending
in both indoor and the out door department of Dermatology and Venereology, CMCH. The
study included 60 patients of diagnosed case of Psoriasis and 60 patients of skin disease
other than psoriasis.
Among the 120 study subjects 72(60%) were male and 48(40%) were female. Male to
female distribution among group A and group B was statistically insignificant (p>0.05). Most
of the patients were in the age group 41-50 years where 24(40%) in group A and 14(23%) in
group B. Mean ± SD of age was 47.78 ± 9.81 years among group A and in group B it was 44.97
± 11.46 years(p>0.05). Mean ± SD of fasting blood sugar was found 102.53 ± 27.67 mg/dl, and
post prandial blood sugar was found 144.75 ± 49.98 mg/dl among the group A patients whereas
it was 92 ± 15.37 mg/dl and 127.20 ± 27.27 mg/dl respectively in group B. Both the distribution
was statistically significant (p<0.05). Among the study subjects DM was found in 26(43.3%) in
group A and 10(16.7%) in group B patients [(OR(CI) =3.824 (1.635 - 8.942), p<0.05), HTN was
found 23(38.3%) in group A and 8(13.3%) in group B [OR (CI)= 4.041 (1.629- 10.020), p<0.05].
In this analysis, Psoriasis was associated with an increased risk of Diabetes
Mellitus and Hypertension. Future studies are needed to find out whether Psoriasis treatment
will reduce the risk of Diabetes Mellitus and Hypertension.
Psoriasis, Risk factor, Diabetes mellitus, Hypertension.
